CORRELATION BETWEEN PROMOTER HYPERMETHYLATION AND EXPRESSION PROFILES OF P15INK4B AND P16INK4A GENES ON DEVELOPMENT OF PTERYGIUM DISEASE

Correlation between Promoter Hypermethylation and Expression Profiles of P15INK4b and P16INK4a Genes on Development of Pterygium Disease

Background: It is not thoroughly clear that what is the exact etiology of pterygium.Recently, it has been illustrated that pterygium is a benign and destructive condition.The aim of this study was to examine the correlation between promoter hypermethylation of P15INK4band P16INK4a genes on progress of pterygium.Materials and methods: We extracted D

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Spatiotemporal dynamics of HSV genome nuclear entry and compaction state transitions using bioorthogonal chemistry and super-resolution microscopy.

We investigated the spatiotemporal dynamics of HSV genome transport during the initiation of infection using viruses containing bioorthogonal traceable precursors incorporated into their genomes (HSVEdC).In Mobile Worktables vitro assays revealed a structural alteration in the capsid induced upon HSVEdC binding to solid supports that allowed coupli

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